Mechanisms
3 pieces tagged Mechanisms.
A Ghost of Progress - How Hierarchies Become Fixtures
I have written extensively on hierarchies of evidence in evidence-based medicine. The origin story of hierarchies of evidence is a little contentious. Several sources in EBM cite Campbell and Stanley's 1963 classic "Experimental and Quasi-experimental Designs for Research" as...
The Dismal Disease: Temozolomide and the Interaction of Evidence
Evidence interacts. To understand the evidence base for an intervention we must look not only at individual studies, but the relationships between them.
The Positivity Machine: "Evidence-Based Alternative Medicine" and Grades of Recommendation
In his beat-poem Storm, the musician and comedian Tim Minchin lays out an apparent paradox. By his criteria, there can never be evidence-based alternative medicine. As soon as there’s evidence that a treatment works, it joins scientific medicine. Minchin goes on to list...